Bioinformatics

Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer.

Authors Kitchen MO, Bryan RT, Emes RD, Glossop JR, Luscombe C, Cheng KK, Zeegers MP, James…
Virulence related sequences; insights provided by comparative genomics of Streptococcus uberis of differing virulence.

Authors Hossain M, Egan SA, Coffey T, Ward PN, Wilson R, Leigh JA, Emes RD. Abstract…
Transposon insertion mapping with PIMMS–pragmatic insertional mutation mapping system.

Authors Blanchard AM, Leigh JA, Egan SA, Emes RD. Abstract The PIMMS (Pragmatic Insertional Mutation Mapping…
TGF-β superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development.

Authors Japa, O., Hodgkinson, J.E., Emes, R.D. and Flynn, R.J. Abstract The helminth Fasciola hepatica causes…
Novel in vitro diagnosis of equine allergies using a protein array and mathematical modelling approach: a proof of concept using insect bite hypersensitivity.

Authors Marti, E., Wang, X., Jambari, N.N., Rhyner, C., Olzhausen, J., Pérez-Barea, J.J., Figueredo, G.P. and…
Methylation of HOXA9 and ISL1 predicts patient outcome in high-grade non-invasive bladder cancer.

Authors Kitchen, M.O., Bryan, R.T., Haworth, K.E., Emes, R.D., Luscombe, C., Gommersall, L., Cheng, K.K., Zeegers,…
MAGE-A cancer/testis antigens inhibit MDM2 ubiquitylation function and promote increased levels of MDM4.

Authors Marcar, L., Ihrig, B., Hourihan, J., Bray, S.E., Quinlan, P.R., Jordan, L.B., Thompson, A.M., Hupp,…
DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS.

Authors Glossop, J.R., Haworth, K.E., Emes, R.D., Nixon, N.B., Packham, J.C., Dawes, P.T., Fryer, A.A., Mattey,…
The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits.

Authors Parameswaran N, Dewals BG, Giles TC, Deppmann C, Blythe M, Vanderplasschen A, Emes RD, Haig…
Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects

Authors Onoufriadis A, Shoemark A, Schmidts M, Patel M, Jimenez G, Liu H, Thomas B, Dixon…