
Publications
Research papers
- ResearchData Science
The feasibility and acceptability of automated feedback and deliberate practice in psychological therapies for anxiety and depression
Authors Sam Malins, Grazziela Figueredo, David Saxon, Kate Horton, Jeremie Clos, Thomas Trimble, Kavan Fatehi, David Waldram, Fred Higton, Gillian E Hardy, Michael Barkham, Jonathan Couldridge and Nima Moghaddam
Deliberate practice (DP) for psychological therapists involves using objective, corrective feedback to identify and improve individualised skill deficits, alongside iterative practice opportunities. Automated, prognostic feedback on session contents could enhance personalisation of DP across…
- ResearchBioinformatics
Genetic diversity of Koala retrovirus env gene subtypes: insights into northern and southern koala populations
Authors Sarker N, Fabijan J, Seddon J, Tarlinton R, Owen H, Simmons G, Thia J, Blanchard AM, Speight N, Kaler J, Emes RD, Woolford L, Trott D, Hemmatzadeh F, Meers J.
Koala retrovirus (KoRV) is a recently endogenized retrovirus associated with neoplasia and immunosuppression in koala populations. The virus is known to display sequence variability and to be present at varying prevalence in different populations, with animals in southern Australia displaying lower…
- ResearchBioinformatics
The Cross-Talk between miR-511-3p and C-Type Lectin Receptors on Dendritic Cells Affects Dendritic Cell Function
Authors Awuah D, Alobaid M, Latif A, Salazar F, Emes RD, Ghaemmaghami AM.
MicroRNAs are small, noncoding RNAs that function as posttranscriptional modulators of gene expression by binding target mRNAs and inhibiting translation. They are therefore crucial regulators of several biological as well as immunological events. Recently, miR-511-3p has been implicated in the…
- ResearchBioinformatics
Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis
Authors Probert C, Dottorini T, Speakman A, Hunt S, Nafee T, Fazeli A, Wood S, Brown JE, James V.
The role of extracellular vesicles (EVs) as vehicles for cell-to-cell communication between a tumour and its environment is a relatively new concept. The hypothesis that EVs may be critical in co-opting tissues by tumours to generate distant metastatic niches is particularly pertinent to prostate…
- ResearchData Science
The Usefulness of Data-driven, Intelligent Agent-Based Modelling for Transport Infrastructure Management.
Authors Faboya, Olusola; Figueredo, Grazziela; Ryan, Brendan; Siebers, Peer-Olaf.
The uneven utilisation of modes of transport has a big impact on traffic in transport pathway infrastrutures. For motor vehicles for instance, this situation explains rapid road deterioration and the large amounts of money invested on maintenance and development due to overuse. There are many…
- ResearchBioinformatics
The Beta-adrenergic agonist, Ractopamine, increases skeletal muscle expression of Asparagine Synthetase as part of an integrated stress response gene program.
Authors Brown D, Ryan K, Daniel Z, Mareko M, Talbot R, Moreton J, Giles TCB, Emes R, Hodgman C, Parr T, Brameld JM.
Synthetic beta-adrenergic agonists (BA) have broad biomedical and agricultural application for increasing lean body mass, yet a poor understanding of the biology underpinning these agents is limiting further drug discovery potential. Growing female pigs (77 ± 7 kg) were administered the BA,…
- ResearchBioinformatics
The applied development of a tiered multilocus sequence typing (MLST) scheme for Dichelobacter nodosus.
Authors Blanchard AM, Jolley KA, Maiden MCJ, Coffey TJ, Maboni G, Staley CE, Bollard NJ, Warry A, Emes RD, Davies PL, Tötemeyer S.
Dichelobacter nodosus ( D. nodosus ) is the causative pathogen of ovine footrot, a disease that has a significant welfare and financial impact on the global sheep industry. Previous studies into the phylogenetics of D. nodosus have focused on Australia and Scandinavia, meaning the current diversity…
- ResearchData Science
Automated detection of lameness in sheep using machine learning approaches: novel insights into behavioural differences among lame and non-lame sheep.
Authors Kaler J, Mitsch J, Vázquez-Diosdado JA, Bollard N, Dottorini T, Ellis KA.
Lameness in sheep is the biggest cause of concern regarding poor health and welfare among sheep-producing countries. Best practice for lameness relies on rapid treatment, yet there are no objective measures of lameness detection. Accelerometers and gyroscopes have been widely used in human activity…
- ResearchResearch Software Engineering
Chaste: Cancer, Heart and Soft Tissue Environment.
Authors Cooper FR, Baker RE, Bernabeu MO, Bordas R, Bowler L, Bueno-Orovio A, Byrne HM, Carapella V, Cardone-Noott L, Jonatha C, Dutta S, Evans BD, Fletcher AG, Grogan JA, Guo W, Harvey DG, Hendrix M, Kay D, Kursawe J, Maini PK, McMillan B, Mirams GR, Osborne JM, Pathmanathan P, Pitt-Francis JM, Robinson M, Rodriguez B, Spiteri RJ, Gavaghan DJ.
Chaste (Cancer, Heart And Soft Tissue Environment) is an open source simulation package for the numerical solution of mathematical models arising in physiology and biology. To date, Chaste development has been driven primarily by applications that include continuum modelling of cardiac…
- ResearchData Engineering
Extending the Minimum Information About Biobank Data Sharing Terminology to Describe Samples, Sample Donors, and Events.
Authors Eklund N, Andrianarisoa NH, van Enckevort E, Anton G, Debucquoy A, Müller H, Zaharenko L, Engels C, Ebert L, Neumann M, Geeraert J, T’Joen V, Demski H, Caboux É, Proynova R, Parodi B, Mate S, van Iperen E, Merino-Martinez R, Quinlan PR, Holub P, Silander K.
Introduction: The Minimum Information About BIobank data Sharing (MIABIS) was initiated in 2012. MIABIS aims to create a common biobank terminology to facilitate data sharing in biobanks and sample collections. The MIABIS Core terminology consists of three components describing biobanks, sample…

